Early Life Adversity, Functional Connectivity And Cognitive Performance In Schizophrenia: The Mediating Role Of IL-6

CONCLUSION: This work suggests that previous associations between CT and social cognition may be partly mediated via an increased inflammatory response. IL-6's association with changes in DMN activity further suggest at least one cortical network via which CT related effects on cognition may be transmitted.PMID:34242739 | DOI:10.1016/j.bbi.2021.06.016

Source: Brain, Behavior, and Immunity - July 9, 2021 Category: Neurology Authors: Sinead King Laurena Holleran David Mothersill Saahithh Patlola Karolina Rokita Ross McManus Marcus Keynon Colm McDonald Brian Hallahan Aiden Corvin Derek Morris John Kelly Declan McKernan Gary Donohoe Source Type: research