Pulsatility Protects the Endothelial Glycocalyx during Extracorporeal Membrane Oxygenation

ConclusionThe maintenance of the PWSS by pulsatility during ECMO possesses beneficial effects on glycocalyx integrity. Moreover, pulsatility prevents EndMT in endothelial cells, and low pulsatility exhibits the best protective effects. The augmentation of pulsatility may be a plausible future direction to improve the clinical outcome in ECMO.

Source: Microcirculation - July 10, 2021 Category: Research Authors: Yu Zhang, Jianfeng Zeng, Xiaoqian He, Weidong Cao, Xiaopeng Peng, Guanhua Li Tags: ORIGINAL ARTICLE Source Type: research