SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer ’s disease

Human tauopathies including Alzheimer ’s disease (AD) are characterized by alterations in the post-translational modification (PTM) pattern of Tau, which parallel the formation of insoluble Tau aggregates, neur...

Source: Molecular Neurodegeneration - July 2, 2021 Category: Neurology Authors: Maria Bichmann, Nuria Prat Oriol, Ebru Ercan-Herbst, David C. Sch öndorf, Borja Gomez Ramos, Vera Schwärzler, Marie Neu, Annabelle Schlüter, Xue Wang, Liang Jin, Chenqi Hu, Yu Tian, Janina S. Ried, Per Haberkant, Laura Gasparini and Dagmar E. Ehrnhoefe Tags: Research article Source Type: research