Hyperprolactinemia after menopause: diagnosis and management

Among hormone-secreting pituitary tumors, prolactinomas are the most common histotype and represent approximately 50% of all pituitary adenomas (1,2). In clinical setting infertility, galactorrhea, gonadal and sexual dysfunction are usually the most relevant clinical features in both sexes (1,2), independently on tumor size at diagnosis, generally microprolactinomas in women and macroprolactinomas in men (1-3). However, in women signs and symptoms of hypogonadism are naturally reported at presentation in fertile age, whereas after menopause these features cannot rate clinical significance taking into account that patients are amenorrheic and fertility is not a major concern.

Source: Maturitas - July 3, 2021 Category: Primary Care Authors: Renata S. Auriemma, Rosa Pirchio, Rosario Pivonello, Annamaria Colao Source Type: research