A new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson ’s disease

Missense variants and multiplications of the alpha-synuclein gene (SNCA) are established as rare causes of autosomal dominant forms of Parkinson ’s Disease (PD).

Source: Parkinsonism and Related Disorders - June 28, 2021 Category: Neurology Authors: Christina Fevga, Yangshin Park, Ebba Lohmann, Anneke J. Kievit, Guido J. Breedveld, Federico Ferraro, Leon de Boer, Rick van Minkelen, Hasmet Hanagasi, Agnita Boon, Wei Wang, Gregory A. Petsko, Quyen Q. Hoang, Murat Emre, Vincenzo Bonifati Source Type: research