Effects of Translumbosacral Neuromodulation Therapy on Gut and Brain Interactions and Anorectal Neuropathy in Fecal Incontinence: A Randomized Study

ConclusionsTNT significantly improves afferent ano-cortical signaling, efferent lumbo-anal and sacro-anal neuropathy and anorectal sensorimotor function. These neurobiologic effects were most prominent with 1  Hz frequency. TNT improves FI by modifying the underlying pathophysiology possibly through neuromodulation.

Source: Neuromodulation: Technology at the Neural Interface - June 22, 2021 Category: Biotechnology Authors: Satish S. C. Rao, Yun Yan, Xuelian Xiang, Amol Sharma, Deepak Ayyala, Shaheen Hamdy Tags: Clinical Research Source Type: research