Assessment of the Effects of a High Amikacin Dose on Plasma Peak Concentration in Critically Ill Children

ConclusionsDespite the administration of the maximal recommended amikacin dose,Cmax was below the pharmacokinetic target in 70% of our pediatric population. Further studies are needed to develop a pharmacokinetic model in a population of critically ill children to optimize target attainment.

http://link.springer.com/10.1007/s40272-021-00456-0

Source: Pediatric Drugs - June 18, 2021 Category: Pediatrics Source Type: research