RUDN University medics detect alterations in amino acid profiles in children with ADHD

(RUDN University) RUDN University doctors found alterations in serum amino acid profile in children with attention deficit hyperactivity disorder (ADHD). The findings will help to understand the mechanism of the disorder and develop new treatment strategies.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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To identify predictors of changes in height, weight, and BMI in children with ADHD starting Central Nervous System (CNS) stimulants.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Original Articles Source Type: research
This study aimed to elucidate to...
Source: BMC Medicine - Category: Internal Medicine Authors: Tags: Research article Source Type: research
Inattention is one of the most significant clinical symptoms for evaluating attention deficit hyperactivity disorder (ADHD). Previous inattention estimations were performed using clinical scales. Recently, predictive models for inattention have been established for brain-behavior estimation using neuroimaging features. However, the performance of inattention estimation could be improved for conventional brain-behavior models with additional feature selection, machine learning algorithms, and validation procedures. This paper aimed to propose a unified framework for inattention estimation from resting state fMRI to improve ...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
BACKGROUND: Bupropion is an antidepressant medication with expanding indications including smoking cessation, weight loss, attention-deficit/hyperactivity disorder, seasonal affective disorder, and amphetamine dependence. Despite its increasing popularity ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
CONCLUSION: Unimodal hypersensitivity seems to have no influence on the integration of basal stimuli, but it might have negative consequences for the multisensory integration of complex stimuli. This finding was supported by observations of higher resting-state functional connectivity between unimodal sensory areas and polymodal multisensory integration convergence zones for complex stimuli.PMID:34548387 | DOI:10.1503/jpn.210017
Source: Journal of Psychiatry and Neuroscience - Category: Psychiatry Authors: Source Type: research
Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHuman genetics have defined a new autism-associated syndrome caused by loss-of-function mutations in MYT1L, a transcription factor known for enabling fibroblast-to-neuron conversions. However, how MYT1L mutation causes autism, ADHD, intellectual disability, obesity, and brain anomalies is unknown. Here, we develop a mouse model of this syndrome. Physically, Myt1l haploinsufficiency causes obesity, white-matter thinning, and microcephaly in the mice, mimicking clinical phenotypes. Studies during brain development reveal disrupted gene exp...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
Contributors : Jiayang Chen ; Joseph DoughertySeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusHuman genetics have defined a new autism-associated syndrome caused by loss-of-function mutations in MYT1L, a transcription factor known for enabling fibroblast-to-neuron conversions. However, how MYT1L mutation causes autism, ADHD, intellectual disability, obesity, and brain anomalies is unknown. Here, we develop a mouse model of this syndrome. Physically, Myt1l haploinsufficiency causes obesity, white-matter thinning, and mi...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing Mus musculus Source Type: research
BACKGROUND: Impulsivity is associated with several psychiatric disorders, including substance use disorders (SUD) and attention deficit hyperactivity disorder (ADHD). A widely used questionnaire to assess impulsivity is the Barratt Impulsiveness Scale (BIS...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
We examined historical trends and factors that may influence population-level patterns in information seeking for attention-deficit/hyperactivity disorder (ADHD). We extracted Google Trends data from January 2004 to February 2020. Keywords included “ADHD,” “ADHD treatment,” “ADHD medication,” and “ADHD therapy.” We examined trends (systematic change over time) and seasonality (repeating pattern of change) via time-series analyses and graphics. We also used interrupted time-series analyses to examine the impact of celebrity and pharmaceutical events. Queries of “ADHD med...
Source: Administration and Policy in Mental Health and Mental Health Services Research - Category: Psychiatry Source Type: research
ConclusionsThere is substantial body of evidence to suggest that MPH is an effective and safe treatment option for adults with ADHD.
Source: Psychopharmacology - Category: Psychiatry Source Type: research
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