Proteomic analyses of plasma-derived exosomes in immunoglobulin (Ig) G4-related disease and their potential roles in B cell differentiation and tissue damage

CONCLUSION: Proteomic profiling revealed that plasma exosome proteins may participate in the pathogenesis of IgG4-RD through complement activation and may be involved in B cell differentiation and activation of the B cell auto-oxidative damage pathway.PMID:34107438 | DOI:10.1016/j.jaut.2021.102650

Source: Journal of Autoimmunity - June 9, 2021 Category: Allergy & Immunology Authors: Panpan Zhang Yusheng Zhang Meng Pan Zheng Liu Jieqiong Li Linyi Peng Jiaxin Zhou Chaojun Hu Shengyun Liu Xiaofeng Zeng Wei Ge Wen Zhang Source Type: research