Quantification of the B6 vitamers in human plasma and urine in a study with pyridoxamine as an oral supplement; pyridoxamine as an alternative for pyridoxine

Vitamin B6 is involved in a large spectrum of physiological processes and comprises of the vitamers pyridoxamine (PM), pyridoxal (PL), pyridoxine (PN), and their phosphorylated derivatives including the biological active pyridoxal 5 ′-phosphate (PLP). While PN toxicity is known to complicate several treatments, PM has shown promise in relation to the treatment of metabolic and age-related diseases by blocking oxidative degradation and scavenging toxic dicarbonyl compounds and reactive oxygen species.

Source: Clinical Nutrition - June 10, 2021 Category: Nutrition Authors: Mathias D.G. Van den Eynde, Jean L.J.M. Scheijen, Coen D.A. Stehouwer, Toshio Miyata, Casper G. Schalkwijk Tags: Original article Source Type: research