Ferulic acid suppresses interleukin ‐1β‐induced degeneration of chondrocytes isolated from patients with osteoarthritis through the SIRT1/AMPK/PGC‐1α signaling pathway

ConclusionOur findings reveal that FA prevents IL-1 β-induced osteoarthritis chondrocyte toxicity, which suggests that FA may be a potential therapy for osteoarthritis and warrants further investigation for its clinical application.

Source: Immunity, Inflammation and Disease - June 2, 2021 Category: Allergy & Immunology Authors: Kewei Du, Xuchen Fang, Ziqiang Li Tags: ORIGINAL ARTICLE Source Type: research