Magnitude of Gluconeogenesis and endogenous glucose production: are they predictable in clinical settings?

Regulation of endogenous glucose production (EGP) is essential for glucose homeostasis. It includes gluconeogenesis (GNG) from non-carbohydrate substrates and hepatic glycogenolysis. Both these pathways are dysregulated in acute stress, but the magnitude of this deregulation cannot be assessed in clinical practice. The study aims at identifying clinically available variables predictive of EGP and GNG magnitude by modeling routinely available data.
Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Original article Source Type: research