Iron robbery by intracellular pathogen via bacterial effector-induced ferritinophagy [Microbiology]

Iron is essential for survival and proliferation of Ehrlichia chaffeensis, an obligatory intracellular bacterium that causes an emerging zoonosis, human monocytic ehrlichiosis. However, how Ehrlichia acquires iron in the host cells is poorly understood. Here, we found that native and recombinant (cloned into the Ehrlichia genome) Ehrlichia translocated factor-3 (Etf-3),...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Microbiology Biological Sciences Source Type: research