Dysregulation of bisphosphoglycerate mutase during in vitro maturation of oocytes

ConclusionHemoglobin and 2,3-BPG may play a role within the maturing COC. This study shows that IVM increases Bpgm within COCs compared to in vivo. Decreasing oxygen concentration and the addition of hemoglobin altered Bpgm, albeit not to levels observed in vivo.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research