Cytogenetic and mutational analysis and outcome assessment of a cohort of 284 children with de novo acute myeloid leukemia reveal complex karyotype as an adverse risk factor for inferior survival

Acute myeloid leukemia (AML) is rare in children. Although complex karyotype (CK) defined as  ≥ 3 cytogenetic abnormalities is an adverse risk factor in adult AML, its prognostic impact on childhood AML remains...

Source: Molecular Cytogenetics - May 19, 2021 Category: Molecular Biology Authors: Xi Chen, Xingjuan Wang, Hu Dou, Zhenzhen Yang, Junqin Bi, Yi Huang, Ling Lu, Jie Yu and Liming Bao Tags: Research Source Type: research