Millifolide A, a dimeric ether of degraded sesquiterpene lactones, inhibited the proliferation of human lung cancer cell line A549

Nat Prod Res. 2021 May 13:1-3. doi: 10.1080/14786419.2021.1922906. Online ahead of print.ABSTRACTThe inhibitory effect of three degraded sesquiterpene lactones, iso-seco-tanapartholide, arteludooicinolide A and millifolide A isolated from Achillea millefolium L., on anti-human lung cancer cells was examined using MTT and reporter gene assays. Millifolide A has significant inhibitory effects on the proliferation of human lung cancer cells probably through inducing cell apoptosis.PMID:33980087 | DOI:10.1080/14786419.2021.1922906

Source: Natural Product Research - May 13, 2021 Category: Biochemistry Authors: Pan-Pan Yu Feng Yu Wen-Zhe Li Si-Ming Wang Chuan Wang Mei Dong Zhi-Yu Ni Yong Li Hiromasa Kiyota Source Type: research