Effects of hypothermia on inflammatory cytokine expression in rat liver following asphyxial cardiac arrest

In conclusion, hypothermic treatment for 4 h following asphyxial CA in rats inhibited the increase of pro-inflammatory cytokines and stimulated the expression of anti-inflammatory cytokines compared with the normothermic group. The results of the present study suggested that hypothermic treatment after asphyxial CA reduced liver damage via the regulation of inflammation.PMID:33968162 | PMC:PMC8097226 | DOI:10.3892/etm.2021.10058

Source: Experimental and Therapeutic Medicine - May 10, 2021 Category: General Medicine Authors: Yoonsoo Park Ji Hyeon Ahn Jeong Hwi Cho Hyun-Jin Tae Tae-Kyeong Lee Bora Kim Jae-Chul Lee Joon Ha Park Myoung Cheol Shin Taek Geun Ohk Jun Hwi Cho Moo-Ho Won Source Type: research