A blood-based diagnostic test incorporating plasma A β42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis

The development of blood-based biomarker tests that are accurate and robust for Alzheimer ’s disease (AD) pathology have the potential to aid clinical diagnosis and facilitate enrollment in AD drug trials. We d...

Source: Molecular Neurodegeneration - May 1, 2021 Category: Neurology Authors: Tim West, Kristopher M. Kirmess, Matthew R. Meyer, Mary S. Holubasch, Stephanie S. Knapik, Yan Hu, John H. Contois, Erin N. Jackson, Scott E. Harpstrite, Randall J. Bateman, David M. Holtzman, Philip B. Verghese, Ilana Fogelman, Joel B. Braunstein and Kev Tags: Research article Source Type: research