Collapsing glomerulopathy in a patient with mixed connective tissue disease

We report a case of a 53-year-old female who presented to us w ith acute kidney injury and proteinuria. The patient underwent renal biopsy for further evaluation of her proteinuria, and was diagnosed to have collapsing glomerulopathy. The patient was subsequently diagnosed with MCTD, given her constellation of symptoms and serology titers. The patient was start ed on prednisone with subsequent stabilization of renal function and reduction of proteinuria and continues to be in remission. We report our case to highlight the association between collapsing glomerulopathy and MCTD and the potential role of steroids as first-line therapy in such cases.
Source: CEN Case Reports - Category: Urology & Nephrology Source Type: research