Prolonged fever - an atypical presentation in mog antibody associated disorders

We report 12 cases of MOG-Ab Associated Disorders (MOGAD) who all manifested prolonged fever (PF) lasting several weeks during the course of the illness. Eight of these had no clinical /imaging evidence of demyelination until much later. Three clinical presentations were: fever of unknown origin (4 /12), aseptic meningitis (4/12) and PF along with established acute demyelination syndrome (4/12). Leukocytosis, and raised inflammatory markers along with CSF pleocytosis were almost universal. The first two presentations frequently caused diagnostic confusion, as MOGAD was not considered until several weeks after disease onset.

Source: Pediatric Neurology - April 2, 2021 Category: Neurology Authors: Vrajesh Udani, Rahul Badheka, Neelu Desai Tags: Short Communication Source Type: research