IL ‐19 ameliorates experimental autoimmune encephalitis

AbstractInterleukin ‐19 (IL‐19) is one of IL‐10 family cytokines that are highly similar to IL‐20 and IL‐241. The receptor of IL ‐19 is the heterodimer of IL‐20 receptor α subunit (IL‐20 Rα) and β subunit (IL‐20Rβ), and its downstream signaling is mediated by STAT3 phosphorylation. Main source of IL‐19 is activated monocyte‐lineage cell including microglia and macrophages1, 2.

Source: Clinical and Experimental Neuroimmunology - March 29, 2021 Category: Neurology Authors: Hideyuki Takeuchi, Hiroshi Horiuchi, Bijay Parajuli, Hiroyasu Komiya, Fumiaki Tanaka, Akio Suzumura Tags: NEW DEVELOPMENTS IN NEUROIMMUNOLOGY Source Type: research