Serrated Polyposis Syndrome: an Update and Review of the Literature

We present an overview on enhancing the identification of patients with serrated polyps (SPs) and serrated polyposis syndrome (SPS), and provide an update on the prevalence and risk of advanced neoplasia in SPS. We finally share recommendations on the endoscopic management of SPS patients and surveillance of first-degree relatives.Recent findingsDetection of patients with SPS can be enhanced by recognizing the clinical criteria; tracking cumulative lifetime size, number, and location of SPs; and designing automated processes to track those polyps. The clinical criteria for SPS were revised in 2019 and provide a framework to risk-stratify patients with SPs who are at a substantially high risk of colorectal cancer (CRC) and require aggressive, yet personalized colonoscopy surveillance.SummarySPS remains underdiagnosed. Automated systems to identify patients with SPS have been shown to increase SPS detection earlier than a clinician. New data suggest that after clearance, a surveillance interval of 1 –3 years appears safe and associated with a low risk of interval CRC.
Source: Current Treatment Options in Gastroenterology - Category: Gastroenterology Source Type: research