The serum protein fetuin-B is involved in the development of acute myocardial infarction

This study may provide a therapeutic advantage for patients at high risk of AMI.
Source: Clinical Science - Category: Biomedical Science Authors: Source Type: research

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This study tests the hypothesis that the lipoxygenase (LOX) pathway mediates protease-activated receptor (PAR) 2-induced activation of the transient receptor potential vanilloid receptor 1 (TRPV1) to protect the heart from ischemia/reperfusion (I/R) injury. SLIGRL, a PAR2 activating peptide, was administered prior to reperfusion following left anterior descending coronary artery ligation in wild type (WT) and TRPV1 knockout (TRPV1-/-) mice. In a Langendorffly perfused heart I/R model, hemodynamic parameters, including left ventricular end-diastolic pressure, left ventricular developed pressure, coronary blood flow and left...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
In conclusion, the present study indicated that puerarin may exhibit antiapoptotic and anti-inflammatory activity through the PPARα pathway in rats with chronic heart failure. PMID: 31602208 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
CONCLUSIONS: Among STEMI patients treated with PCI, the presence of SCH is common and may serve as a significant marker for AKI. PMID: 31599513 [PubMed - in process]
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
BEST supplements for cholesterol: Having high levels of cholesterol is very dangerous to one ’s health. Having high levels of LDL cholesterol increases a person’s chance of having a heart attack and stroke. To keep cholesterol levels healthy, taking these supplements could help to keep you healthy and reduce your risk of serious medical problems.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
Conclusions: The findings of this meta-analysis study suggested that TEVAR resulted in more short-term survival benefits. Moreover, the reduced risk of acute renal failure, respiratory failure and bleeding was detected in TEVAR group. The treatment effects of TEVAR versus OCSR on specific complications should be further verified by a study with high-level of evidence. Key message Comprehensive collected studies investigated the treatment effectiveness between TEVAR and OCSR for TBAD patients TEVAR resulted in more survival benefits, in addition to lower risk of acute renal failure, respiratory failure and bleeding The resu...
Source: Annals of Medicine - Category: Internal Medicine Tags: Ann Med Source Type: research
The first patient has been enrolled in Penumbra’s CHEETAH post-market study to evaluate the Indigo System with CAT RX Aspiration Catheter in the coronary vessels. About 400 patients are expected to be enrolled at 25 centers in CHEETAH. Alameda, CA-based Penumbra’s Indigo System uses mechanical power aspiration to remove thrombus in the coronaries. The primary study endpoint is a composition of cardiovascular (CV) death, recurrent myocardial infarction (MI), cardiogenic shock or new or worsening New York Heart Association (NYHA) Class IV heart failure within 30 days. Secondary endpoints i...
Source: MDDI - Category: Medical Devices Authors: Tags: Cardiovascular Business Source Type: news
HEART attack is an urgent medical condition. Certain health factors may increase a person ’s risk. Recent research has shed a surprising light on the link between oral disease and cardiovascular disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 9 October 2019Source: Seminars in Cell &Developmental BiologyAuthor(s): Michael A. Flinn, Brian A. Link, Caitlin C. O’MearaAbstractThe response of the adult mammalian heart to injury such as myocardial infarction has long been described as primarily fibrotic scarring and adverse remodeling with little to no regeneration of cardiomyocytes. Emerging studies have challenged this paradigm by demonstrating that, indeed, adult mammalian cardiomyocytes are capable of completing cytokinesis albeit at levels vastly insufficient to compensate for the loss of functional cardiomyocytes foll...
Source: Seminars in Cell and Developmental Biology - Category: Cytology Source Type: research
ACS Applied Materials&InterfacesDOI: 10.1021/acsami.9b12043
Source: ACS Applied Materials and Interfaces - Category: Materials Science Authors: Source Type: research
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