High dose expression of heme oxigenase-1 induces retinal degeneration through ER stress-related DDIT3

Oxidative stress is a common cause of neurodegeneration and plays a central role in retinal degenerative diseases. Heme oxygenase-1 (HMOX1) is a redox-regulated enzyme that is induced in neurodegenerative dise...

Source: Molecular Neurodegeneration - March 10, 2021 Category: Neurology Authors: Huirong Li, Bo Liu, Lili Lian, Jiajia Zhou, Shengjin Xiang, Yifan Zhai, Yu Chen, Xiaoyin Ma, Wencan Wu and Ling Hou Tags: Research article Source Type: research