Prediction of Plasma Concentrations Using In Silico Modelling and Simulation Approach: Case of Acebutolol

Conclusion Based on the in vitro results combined with in silico simulations using GastroPlusTM, a biowaiver for immediate release acebutolol tablets is justified. Furthermore, computer modelling has shown to be a very intersting tool to prove the bioequivalence for these products.PMID:33675740 | DOI:10.1016/j.pharma.2021.02.004
Source: Annales Pharmaceutiques Francaises - Category: Drugs & Pharmacology Authors: Source Type: research