Analysis of the Immunoexpression of Opioid Receptors and their Correlation with Markers of Angiogenesis, Cell Proliferation and Apoptosis in Breast Cancer

CONCLUSION: The κ-opioid receptor has a lower immunoexpression in nodal tumor metastasis with recurrence, whereas the μ-opioid receptor is directly related to expression of TUNEL-positive cells in tumors and indirectly to Ki-67 in nodal metastasis. Neither of the two receptors was expressed in the primary tumor or nodal metastasis in relation to VEGF.PMID:33639684 | DOI:10.31557/APJCP.2021.22.2.633

Source: Asian Pacific Journal of Cancer Prevention - February 28, 2021 Category: Cancer & Oncology Authors: Alceu Machado De Sousa Thinali Sousa Dantas Paulo Goberl ânio De Barros Silva Concei ção Da Silva Martins Gildenio Estevam Freire Howard Lopes Ribeiro Junior Gerly Anne De Castro Brito Karuza Maria Alves Pereira Renata Ferreira De Carvalho Leit ão Source Type: research