Associations between insomnia and reward learning in clinical depression

CONCLUSIONS: Among individuals with depression, insomnia is associated with decreased ability to learn associations between neutral stimuli and rewarding outcomes and/or modify behavior in response to differential receipt of reward. This attenuated reward learning may contribute to clinically meaningful decreases in motivation and increased withdrawal in this comorbid group. Results extend existing theory by highlighting impairments in reward learning specifically as a potential mediator of the association between insomnia and depression.PMID:33634765 | DOI:10.1017/S003329172100026X

Source: Psychological Medicine - February 26, 2021 Category: Psychiatry Authors: Gabrielle I Liverant Kimberly A Arditte Hall Sarah T Wieman Suzanne L Pineles Diego A Pizzagalli Source Type: research