Progressive gammopathy and coagulopathy in a young English bulldog

Can Vet J. 2021 Feb;62(2):160-166.ABSTRACTA restricted polyclonal or biclonal gammopathy resulting in bleeding tendencies was diagnosed in a young, neutered male English bulldog with concurrent splenomegaly, anemia, and severe elevations in IgM and, to a lesser degree, IgA immunoglobulins. There was a positive clinical response to treatment with prednisone and chlorambucil. This case bears similarity to a recently published syndrome of polyclonal gammopathy that is not neoplastic in origin in this breed. Key clinical message: The current case describes the management and clinical course of a recently described syndrome of polyclonal gammopathy in English bulldogs.PMID:33542555 | PMC:PMC7808204

Source: The Canadian Veterinary Journal - February 5, 2021 Category: Veterinary Research Authors: Jennifer L Grady Anne Avery A Russell Moore Lauren J Harris Neketa Kakar Emily D Rout Source Type: research