Scientists use machine-learning approach to track disease-carrying mosquitoes

(Utah State University) A team of researchers from Utah State University, University of California, Davis and Yale University are using a machine-learning approach to map landscape connectivity of the species Aedes aegypti, the so-called Yellow Fever mosquito, which is a primary vector for transmission of viruses causing dengue fever, chikungunya and Zika.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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Abstract Genus Flavivirus, which includes 53 virus species, is the leading cause of arthropod-borne diseases in humans. Diagnosis of these viral diseases is complicated by their overlapping epidemiology and clinical manifestations, and the fact that cross-reactive antibody responses are frequently elicited by individuals in response to infection. We developed a bead-based immunoassay to concomitantly profile the isotype and subclass of antibody responses (five isotypes and four subclasses) in parallel with specificity against multiple antigens. Our panel included 22 envelope (E) and non-structural 1 (NS1) proteins...
Source: Journal of Immunological Methods - Category: Allergy & Immunology Authors: Tags: J Immunol Methods Source Type: research
es SG Abstract Zika and Dengue viruses present considerable immunological cross-reactivity, resulting in a troublesome serodiagnosis due to occurrence of false positive results. Due to Brazil's wide variety of circulating flaviviruses we aimed to access the use of in house serological tests adapted by National Reference Laboratory for Arboviruses in Brazil and evaluate commercial tests available. We evaluated in house IgM ELISAs for the individual detection of anti-ZIKV, -DENV, and -YFV IgM, against a panel of samples positive for dengue, zika, yellow fever, Rocio, Ilheus, Saint Louis encephalitis, West Nile and c...
Source: Journal of Virological Methods - Category: Virology Authors: Tags: J Virol Methods Source Type: research
Abstract Viruses were identified from male anthropophilic mosquitoes from Mato Grosso (MT) State, Midwest Brazil from February 2017 to January 2018. Mosquitoes tested included Aedes (Stegomyia) aegypti (1139 males; 84 pools), Culex quinquefasciatus (9426 males; 179 pools), Culex sp. (3 males; 3 pools) and Psorophora albigenu (1 male; 1 pool) collected from four cities of MT. Pools were subjected to viral RNA extraction followed by RT-PCRs specific for ten flaviviruses, five alphaviruses and Simbu serogroup of orthobunyaviruses. Positive pools were passaged three times in VERO cells (alphavirus and orthobunyavirus)...
Source: Infection, Genetics and Evolution - Category: Genetics & Stem Cells Authors: Tags: Infect Genet Evol Source Type: research
Background: From 1995 till 2019, around 147,200 cases of dengue infection and more than 800 deaths are reported from Pakistan. Vector of dengue virus is mosquito Aedes which is capable of transmitting other viral infections like Chikungunya, Zika, and Yellow Fever. From 2016 –2018, Chikungunya infection was reported in 776 patients. With exponential increase in population and utilization of resources, it is important to eradicate this mosquito.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 0631 Source Type: research
Abstract This review focused on the toxicity of essential oils and their constituents against Aedes aegypti L. (Diptera, Culicidae) larvae, a key vector of important arboviral diseases, such as dengue, chikungunya, zika, and yellow fever. This review is based on original articles obtained by searching major databases in the last six years. Our literature review shows that 337 essential oils from 225 plant species have been tested for larvicidal bioactivity. More than 60% of these essential oils were considered active (LC50
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
In the last decades, a number of infectious viruses have emerged from wildlife or re-emerged, generating serious threats to the global health and to the economy worldwide. Ebola and Marburg hemorrhagic fevers, Lassa fever, Dengue fever, Yellow fever, West Nile fever, Zika, and Chikungunya vector-borne diseases, Swine flu, Severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and the recent Coronavirus disease 2019 (COVID-19) are examples of zoonoses that have spread throughout the globe with such a significant impact on public health that the scientific community has been called for a rapid int...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
ila S. Espindola The number of documented dengue cases has increased dramatically in recent years due to transmission through the Aedes aegypti mosquito bite. Vector control remains the most effective measure to protect against this and other arboviral diseases including Zika, chikungunya and (urban) yellow fever, with an established vaccine only available for yellow fever. Although the quinone class shows potential as leading compounds for larvicide development, limited information restricts the development of optimized structures and/or formulations. Thus, in this contribution we investigated the larvicidal and pupic...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
by Shuzhen Sim, Lee Ching Ng, Steve W. Lindsay, Anne L. Wilson Vector-borne diseases are a major cause of morbidity and mortality worldwide.Aedes-borne diseases, in particular, including dengue, chikungunya, yellow fever, and Zika, are increasing at an alarming rate due to urbanisation, population movement, weak vector control programmes, and climate change. The World Health Organization calls for strengthening of vector control programmes in line with the Global Vector Control Response (GVCR) strategy, and many vector control programmes are transitioning to this new approach. The Singapore dengue control programme, situa...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
[Malaria Consortium] On World Mosquito Day, Malaria Consortium calls for the international community to reflect on the devasting impact the mosquito has on global health. In 2018, there were over 228 million malaria cases throughout the world and a global death toll of 405,000. But mosquitoes are responsible for transmitting more than just malaria - from zika virus to yellow fever, dengue, chikungunya, Japanese encephalitis and many more - collectively adding another 500 million cases of people burdened with febrile disease ea
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
by Sarah Guth, Kathryn A. Hanley, Benjamin M. Althouse, Mike Boots Pathogens originating from wildlife (zoonoses) pose a significant public health burden, comprising the majority of emerging infectious diseases. Efforts to control and prevent zoonotic disease have traditionally focused on animal-to-human transmission, or “spillover.” However, in the modern er a, increasing international mobility and commerce facilitate the spread of infected humans, nonhuman animals (hereafter animals), and their products worldwide, thereby increasing the risk that zoonoses will be introduced to new geographic areas. Imported ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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