Starting from the beginning may lead to better outcomes for lupus

Lupus is a chronic autoimmune disorder that causes inflammation and pain throughout the body. Most common in women (9 of 10 diagnosed cases); it attacks both joints and organs - including the skin. Lupus is not curable, but symptoms can be managed with medications. Researchers hope to learn more about lupus and identify ways to predict [...]
Source: Mayo Clinic Research News - Category: Research Source Type: news

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HORSHAM, PA, September 30, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved SIMPONI ARIA® (golimumab) for patients 2 years of age and older for the treatment of active pJIA and has extended the PsA indication for this same patient population. “This latest FDA approval of SIMPONI ARIA for pediatric use in active pJIA and active PsA not only brings a new option to young patients living with these diseases but also adds to the growing body of evidence for this treatment,” said Mathai Mammen, M.D., Ph.D., Glob...
Source: Johnson and Johnson - Category: Pharmaceuticals Source Type: news
Title: Companion Drug Might Help Prevent Kidney Complications of LupusCategory: Health NewsCreated: 9/16/2020 12:00:00 AMLast Editorial Review: 9/17/2020 12:00:00 AM
Source: MedicineNet Chronic Pain General - Category: Anesthesiology Source Type: news
Abstract OBJECTIVES: The purpose of this study was to characterize the impact of cutaneous lupus erythematosus (CLE) in adults and identify the clinical and non-clinical factors associated with quality of life (QoL), using the Revised Wilson and Cleary Model. METHODS: 101 patients diagnosed with CLE were included in this cross-sectional study. QoL was measured with the Cutaneous Lupus Erythematosus Quality of Life (CLEQoL) scale and disease activity and damage with the Cutaneous Lupus Activity and Severity Index (CLASI). Patient demographics, clinical, and disease characteristics were also collected. Descript...
Source: Lupus - Category: Rheumatology Authors: Tags: Lupus Source Type: research
We report a case of a young female patient with a long and complicated history of SLE. She presented with widespread pain and tenderness associated with multiple subcutaneous skin lesions. She was found to have evidence of calcinosis universalis on X-rays. Investigations did not reveal any associated conditions that could explain this diagnosis other than her prolonged history of SLE. PMID: 32693683 [PubMed - as supplied by publisher]
Source: Lupus - Category: Rheumatology Authors: Tags: Lupus Source Type: research
Sensory ganglionopathies (SG) are a rare heterogenous subgroup of neuropathies characterized by primary involvement of sensory neurons in dorsal root ganglions (DRGs) resulting in a distinctive clinical presentation. The onset is usually subacute or chronic with asymmetric, non –length-dependent sensory impairment and ataxia (when large-fiber neurons affected) and/or positive sensory symptoms such as burning pain, hyperesthesia and allodynia (when small-medium size neurons affected) with relatively well-preserved muscle strength.
Source: Neuromuscular Disorders - Category: Neurology Authors: Tags: Case report Source Type: research
Discussion Peritoneal fluid is normal. It decreases the friction of the peritoneum covering abdominal and pelvic organs and helps to protect them and allow their movement. A normal amount of peritoneal fluid is expected on radiological evaluation. Increased peritoneal fluid is a continuum and is concerning as a wide variety of pathological causes are associated with it such as abdominal trauma and appendicitis. At the far end of the scale is ascites that is the accumulation of free fluid more than 25 ml. It is usually associated with abdominal distension but fluid must accumulate before distension can occur and therefore i...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
The healing power of ultraviolet light (UV) has flown under the radar for decades. Yet, it’s one of the most powerful detoxifying agents known to man. It kills bacteria and viruses and can be used in a clinical setting. The therapeutic benefits of light have been known for millennia. Hippocrates, the father of modern medicine, believed light was essential to balance the body and emotions. And there is good reason why, during the Spanish flu pandemic of 1918, medics discovered that severely ill patients had hugely better recovery rates when they were nursed outside and had regular exposure to sunlight.1 You see, UV r...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Health Source Type: news
Title: How Do You Get Lupus?Category: Diseases and ConditionsCreated: 5/21/2020 12:00:00 AMLast Editorial Review: 5/21/2020 12:00:00 AM
Source: MedicineNet Chronic Pain General - Category: Anesthesiology Source Type: news
HORSHAM, PA, April 24, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson today announced the submission of two supplemental Biologics License Applications (sBLA) to the U.S. Food and Drug Administration (FDA) seeking approval of SIMPONI ARIA® (golimumab) for the treatment of polyarticular juvenile idiopathic arthritis (pJIA) and juvenile psoriatic arthritis (jPsA), in patients two years of age and older in combination with methotrexate. If approved for these indications, SIMPONI ARIA would be the first anti-tumor necrosis factor (TNF)-alpha biologic agent administered by intravenous infusion ava...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Conclusions: An early diagnosis and the prompt therapeutic measures are necessary to prevent sight-threatening consequences, especially in pediatric patients with SLE.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
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