FGF21 and Chronic Kidney Disease

The global nephrology community recognizes the increasing burden of kidney disease and its poor health outcomes in the general population. Given this, strategies to establish early diagnosis, improve understanding of the natural course and develop novel therapeutic interventions to slow progression and reduce complications are encouraged. Fibroblast growth factor 21 (FGF21), a member of the endocrine FGF subfamily, has emerged as a master homeostasis regulator of local and systemic lipid, glucose and energy metabolism.

Source: Metabolism - Clinical and Experimental - February 19, 2021 Category: Biomedical Science Authors: Jo ão Victor Salgado, Miguel Angelo Goes, Natalino Salgado Filho Source Type: research