Effects of site, cerebral perfusion and degree of cerebral artery stenosis on cognitive function

Objective

To investigate the effects of site, cerebral perfusion and degree of cerebral artery stenosis (CAS) on cognitive function.

Methods

A total of 57 patients with CAS and 53 controls from January 2019 to December 2019 were included. The former group was further divided into different subgroups according to the site, cerebral perfusion and degree of CAS. A series of neuropsychological tests were performed to evaluate the cognitive domains (such as memory, executive function, psychomotor speed, etc.). Rank sum test, t test, Chi-square test and analysis of variance were used for data analysis. Spearman correlation analysis was used to examine the relationship between the site, cerebral perfusion and degree of CAS and all tests’ scores.

Results

For patients with CAS who have decreased cerebral perfusion, their global cognitive function, memory, psychomotor speed, executive function and frontal lobe function were significantly impaired (all P

Source: NeuroReport - February 3, 2021 Category: Neurology Tags: Integrative Systems Source Type: research