The gut microbiota metabolite propionate ameliorates intestinal epithelial barrier dysfunction-mediated Parkinson’s disease via the AKT signaling pathway

Conclusion Our results demonstrated that propionate, which was decreased in the fecal samples of Parkinson’s disease patients, exerted beneficial effects on intestinal epithelial barrier function and improved motor behavior in MPTP-induced Parkinson’s disease mice through the AKT signaling pathway.
Source: NeuroReport - Category: Neurology Tags: Degeneration and Repair Source Type: research