The role of combined ion-beam radiotherapy (CIBRT) with protons and carbon ions in a multimodal treatment strategy of inoperable osteosarcoma

Osteosarcoma is the most prevalent malignant bone tumor in children and adolescents and is rarely seen in adults. Most osteosarcomas arise at the distal femur and the proximal tibia, and are treated with a regimen of chemotherapy and surgery. While chemotherapy controls micrometastases, surgery controls the primary tumor. There is a substantial number of patients with axial primary tumors (5-10%), which are non-resectable without unacceptable mutilation and thus have significantly reduced long term survival chances [1-3].

Source: Radiotherapy and Oncology - February 4, 2021 Category: Radiology Authors: K. Seidensaal, M. Mattke, S. Haufe, H. Rathke, U. Haberkorn, N. Bougatf, A. Kudak, C. Blattmann, S. Oertel, M. Kirchner, C. Buesch, M. Kieser, K. Herfarth, A. Kulozik, J. Debus, M. Uhl, S.B. Harrabi Tags: Original Article Source Type: research