Moffitt researchers identify how cancer cells adapt to survive harsh tumor microenvironments

(H. Lee Moffitt Cancer Center& Research Institute) To better understand the conditions that select for the Warburg Effect and the mechanisms where cells can express this metabolic adaptation, Moffitt researchers subjected nonmalignant cells to the harsh tumor microenvironment that is present during early carcinogenesis, known as ductal carcinoma in situ. In a new research article published in the Proceedings of the National Academy of Sciences, the Moffitt team shows that these conditions select for cells to express a Warburg Effect.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news