Use of probiotics in the treatment of functional abdominal pain in children —systematic review and meta-analysis

Conclusion: Based on the available evidence, no firm conclusions can be given; however,L. reuteri was proven to decrease the pain intensity in children with functional abdominal pain. Further trials regarding long-term outcomes, possibly involving longer interventions, are needed.What is Known:•Previously published systematic reviews have suggested that probiotics may have an effect on the pain in children with functional gastrointestinal disorders, but limited data exist on strain-specific effects.What is New:•This systematic review provides evidence on the probiotic use on the strain-specific level.•This systematic review showed that the use of Lactobacillus reuteri DSM 17938 modestly reduces the pain intensity in children with functional abdominal pain.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research