Accelerator Production of Scandium Radioisotopes: Sc-43, Sc-44, and Sc- 47.

Accelerator Production of Scandium Radioisotopes: Sc-43, Sc-44, and Sc- 47. Curr Radiopharm. 2021 Jan 12;: Authors: Chernysheva M, Loveless SC, Brossard T, Becker K, Cingoranelli S, Aluicio-Sarduy E, Song J, Ellison P, Nolen J, Rotsch DA, Lapi SE, Engle JW Abstract Scandium radioisotopes are increasingly considered viable radiolabels for targeted molecular imaging (Sc-43, Sc-44) and therapy (Sc-47). Significant technological advances have increased the quantity and quality of available radioscandium in the past decade, motivated in part by the chemical similarity of scandium to therapeutic radionuclides like Lu-177. The production and radiochemical isolation techniques applied to scandium radioisotopes are reviewed, focusing on charged particle and electron linac initiated reactions and using calcium and titanium starting materials. PMID: 33438551 [PubMed - as supplied by publisher]
Source: Current Radiopharmaceuticals - Category: Radiology Tags: Curr Radiopharm Source Type: research