Trends and Outcomes of Transcatheter Valve Implantation in Patients with Prior Mediastinal Radiation

Transcatheter aortic valve implantation (TAVI) is a safe and effective alternative for patients with severe aortic stenosis (AS) irrespective of their surgical risk.1, 2 Aortic stenosis is the most common radiation-induced valvular heart disease. Surgical aortic valve replacement is associated with higher operative mortality and morbidity among patients with prior mediastinal radiation. 3 While a percutaneous approach appears appealing for patients with prior mediastinal radiation, these patients were excluded from pivotal randomized trials.

Source: The American Journal of Cardiology - January 13, 2021 Category: Cardiology Authors: Ayman Elbadawi, Islam Y. Elgendy, Aiham Albaeni, Ahmed Sobhy, Ahmad Almustafa, Hend I. Shahin, Arka Chatterjee, Mohamad Alkhouli, Wissam Khalife, Samir Kapadia, Hani Jneid Source Type: research