Connective tissue diseases: Adipocyte–myofibroblast transition: linking intradermal fat loss to skin fibrosis in SSc

Nature Reviews Rheumatology 11, 63 (2015). doi:10.1038/nrrheum.2014.223 Author: Sarah Onuora Myofibroblasts are considered the primary fibrogenic effector cells in systemic sclerosis (SSc), but the origin of these cells within fibrotic lesions is a matter of debate. A new study published in Arthritis & Rheumatology shows that the majority of dermal myofibroblasts in fibrotic skin
Source: Nature Reviews Rheumatology - Category: Rheumatology Authors: Tags: Research Highlight Source Type: research