Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats.

CONCLUSIONS: An aortic dissection model with a high incidence and low mortality was successfully and stably developed with 0.08% β-aminopropionitrile. This model will enable further studies investigating aortic dissection pathogenesis and drug therapy. Magnetic resonance imaging may be a reliable technique for imaging the aorta in rats.
PMID: 33357159 [PubMed - as supplied by publisher]

Source: Vascular - December 23, 2020 Category: Surgery Authors: Lv X, Hu Y, Chen X, Chen X, Chen L, Lin Y, Hou Y Tags: Vascular Source Type: research