Completion and adverse drug events of latent tuberculosis infection treatment in patients receiving dialysis: predictors and impacts of different regimens in a prospective cohort study.

CONCLUSIONS: For patients on dialysis, 3HP showed a higher rate of completion but also a higher rate of ≥grade 2 ADE than 9H. In addition, DM and PD were risk for ≥grade 2 ADE. Eosinophilia after 2-week treatment might be an alert for severe ADE.
PMID: 33361292 [PubMed - as supplied by publisher]

Source: Antimicrobial Agents and Chemotherapy - December 23, 2020 Category: Microbiology Authors: Lin SY, Feng JY, Lee CY, Lin YC, Chou YH, Lin KY, Wei YF, Lin SW, Chang CH, Wang PH, Shu CC, Wang JY, Yu CJ Tags: Antimicrob Agents Chemother Source Type: research