Anisotropic Conduction and Re-entry in the Heart

Following the seminal paper by Madison Spach and Mark Josephson, clinicians have been aware of anisotropic re-entry as an established mechanism of arrhythmogenesis, although the exact mechanisms responsible remain uncertain.1 Nevertheless, changes in microanatomical structures, such as cellular coupling, gap junction distribution and function and fibre disarray, lead to anisotropic conduction, i.e.

Source: Radcliffe Cardiology - December 24, 2020 Category: Cardiology Source Type: research