Feasibility of next ‐generation sequencing test for patients with advanced NSCLC in clinical practice

ConclusionsThe feasibility of Oncomine Dx in clinical practice was lower than the other CDx. The feasibility of Oncomine Dx will increase by improving the biopsy procedure.Key pointsSignificant study findings
The usefulness of a next ‐generation sequencing (NGS) test has been proven in clinical trials.
The feasibility of NGS is lower than other diagnostics in clinical practice especially with regard to nonsurgical biopsy.What this study adds
It is necessary to improve the feasibility of NGS in clinical practice.
To improve NGS feasibility, turnaround time must be shortened, and larger samples must be obtained during surgical procedures.

Source: Thoracic Cancer - December 21, 2020 Category: Cancer & Oncology Authors: Ryo Ariyasu, Ken Uchibori, Hironori Ninomiya, Shinsuke Ogusu, Ryosuke Tsugitomi, Ryo Manabe, Hiroaki Sakamaoto, Takehiro Tozuka, Hiroshi Yoshida, Yoshiaki Amino, Satoru Kitazono, Noriko Yanagitani, Kengo Takeuchi, Makoto Nishio Tags: ORIGINAL ARTICLE Source Type: research