2.5-fold increased risk of recurrent acute myocardial infarction with familial hypercholesterolemia

A first-time acute myocardial infarction (AMI) is a severe diagnosis that leads to initiation or intensification of lipid-lowering medication to prevent recurrent events. Individuals with familial hypercholesterolemia (FH) already use high-intensity lipid-lowering medication at the time of an incident AMI due to their diagnosis. Hence, we hypothesized that compared with matched non-FH controls, individuals with genetically verified FH have increased mortality and risk of recurrent AMI after their first event.

Source: Atherosclerosis - December 21, 2020 Category: Cardiology Authors: Karianne Svendsen, Henriette W. Krogh, Jannicke Igland, Grethe S. Tell, Liv J. Mundal, Kirsten B. Holven, Martin P. Bogsrud, Trond P. Leren, Kjetil Retterst øl Source Type: research