Interleukin-18 is a sensitive marker of flair initiation in Adamantiades-Beh çet's disease.

Interleukin-18 is a sensitive marker of flair initiation in Adamantiades-Behçet's disease. Br J Dermatol. 2020 Dec 17;: Authors: Zouboulis CC, Altenburg A Abstract Adamantiades-Behçet's disease (ABD; MIM 109650) is a rare, neutrophilic vascular reaction or vasculitis with a chronic recurrent progressive course leading to systemic inflammatory vascular disease with potentially severe prognosis.1 Its aetiology remains unknown. A genetic predisposition, triggered by infection/environmental factor(s) leading to hyperergic immunological reaction/damage of the vascular endothelium is assumed. A responsible gene locus is probably located on chromosome 6 short arm (6p21.3) inside the major histocompatibility complex area. PMID: 33332577 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research