Phospholipid Analogues as Chemotherapeutic Agents Against Trypanoso matids.

CONCLUSION: Phospholipid analogues are already known for their antiprotozoal activity. Several studies have been conducted in order to synthesize novel derivatives with the aim to improve current treatments such as miltefosine, with promising results. Photolabeling and fluorescent alkyl phospholipid analogues have contributed to the clarification of the mode of action of this drug family.
PMID: 33302850 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Design - December 9, 2020 Category: Drugs & Pharmacology Authors: Chazapi E, Magoulas GE, Prousis KC, Calogeropoulou T Tags: Curr Pharm Des Source Type: research