Ambrosin sesquiterpene lactone exerts selective and potent anticancer effects in drug-resistant human breast cancer cells (MDA-MB-231) through mitochondrial mediated apoptosis, ROS generation and targeting Akt/ β-Catenin signaling pathway.

CONCLUSIONS: Taken all together, the results of our study indicate that ambrosin sesquiterpene may be developed as a promising anticancer agent in human breast cancer provided further in-depth studies are performed. PMID: 33277839 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33277839?dopt=Abstract

Source: Journal of B.U.ON. - December 7, 2020 Category: Cancer & Oncology Tags: J BUON Source Type: research