Prostaglandins as potential targets for the treatment of polycystic kidney disease

Polycystic kidney disease (PKD) encompasses a group of disorders characterized by the proliferation of fluid-filled renal cysts. These cysts cause progressive damage to the normal renal parenchyma, which ultimately leads to progressive renal failure. The most common form of PKD and the most common monogenetic cause of any renal disease is autosomal dominant PKD (ADPKD), which in the past was referred to as adult PKD, since renal failure typically occurs later in life. Another form of the disease, which is much less common but more severe, is autosomal recessive PKD that affects the pediatric population.

Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - November 25, 2020 Category: Biomedical Science Authors: Harold M. Aukema Source Type: research