Recent progresses in marine microbial-derived antiviral natural products.

Recent progresses in marine microbial-derived antiviral natural products. Arch Pharm Res. 2020 Nov 21;: Authors: Teng YF, Xu L, Wei MY, Wang CY, Gu YC, Shao CL Abstract Viruses have always been a class of pathogenic microorganisms that threaten the health and safety of human life worldwide. However, for a long time, the treatment of viral infections has been slow to develop, and only a few antiviral drugs have been using clinically. Compared with these from terrestrial environments, marine-derived microorganisms can produce active substances with more novel structures and unique functions. From 2015 to 2019, 89 antiviral compounds of 8 structural classes have been isolated from marine microorganisms, of which 35 exhibit anti-H1N1 activity. This review surveys systematically marine microbial-derived natural products with antiviral activity and illustrates the impact of these compounds on antiviral drug discovery research. PMID: 33222073 [PubMed - as supplied by publisher]
Source: Archives of Pharmacal Research - Category: Drugs & Pharmacology Authors: Tags: Arch Pharm Res Source Type: research