Global REACH 2018: Regional differences in cerebral blood velocity control during normoxic and hypoxic cold pressor tests.

Global REACH 2018: Regional differences in cerebral blood velocity control during normoxic and hypoxic cold pressor tests. Auton Neurosci. 2020 Nov 04;229:102740 Authors: Tymko MM, Hoiland RL, Ainslie PN Abstract The impact of oxygen on the cerebral response to the cold pressor test (CPT) remains unknown. In 13 participants, blood pressure, middle and posterior cerebral artery blood velocity (MCAv and PCAv, respectively) were measured during an isocapnic normoxic and hypoxic (SpO2 = 85%) CPT. The main findings were: 1) the MCAv response to the CPT was greater compared to the PCAv in both normoxic and hypoxic conditions (P = 0.003 and P = 0.002, respectively); and, 2) hypoxia did not alter the cerebral response to the CPT (P = 0.141 and P = 0.150, respectively). These data highlight that regional differences in cerebrovascular control exist during the CPT. PMID: 33166837 [PubMed - as supplied by publisher]
Source: Autonomic Neuroscience - Category: Neuroscience Authors: Tags: Auton Neurosci Source Type: research